6-MP
6-MP belongs to the anticancer medicine class, which is used to treat blood cancer. Leukemia, or blood cancer, is a malignancy of the blood cells. It causes the bone marrow to produce an excessive amount of immature white blood cells.
6-MP includes Mercaptopurine, which inhibits the formation of genetic material (DNA and RNA) in cancer cells, which is required for cell development, repair, and reproduction. Thus, 6-MP inhibits aberrant cell multiplication and produces uneven cell growth, ultimately leading to cell death.
Follow your doctor’s instructions for taking 6-MP. You should continue to take 6-MP for as long as your doctor has prescribed it for your medical condition. You may experience nausea, vomiting, low red blood cell count, loss of appetite, diarrhea, or mouth inflammation in some circumstances. The majority of 6-MP’s negative effects do not require medical treatment and fade away with time. Please visit your doctor if the side effects persist or worsen.
Please inform your doctor if you are allergic to 6-MP or any other medications. If you’re pregnant or breastfeeding, avoid taking 6-MP and talk to your doctor. To avoid conception, you should use an effective contraceptive technique while taking 6-MP and for 3 months after finishing the course. 6-MP should be taken with caution in children, especially those under the age of six or those with a low BMI, as it can produce low blood sugar. Avoid extensive sun exposure since 6-MP can induce photosensitivity. When going out, it is recommended that you use a high-factor sunscreen and wear protective gear. 6-MP may raise the risk of macrophage activation syndrome (overactivation of white blood cells associated with inflammation), a dangerous illness that affects persons with arthritis.
6-MP Applications
Cancer of the blood (Acute lymphoblastic leukemia)
Medical Advantages
Mercaptopurine, an anticancer medication used to treat blood cancer, is included in 6-MP. 6-MP inhibits the creation of genetic material (DNA and RNA) in cancer cells, which is required for cell development, repair, and multiplication. As a result, 6-MP inhibits the expansion of aberrant cells, causing imbalanced cell growth and cell death.
Use Instructions
Take 6-MP with or without food, preferably 1 hour before or 2 hours after eating milk or dairy products, as directed by your doctor. 6-MP tablets should be consumed whole, along with a glass of water. It should not be broken, crushed, or chewed. The liquid form of 6-MP should be taken by mouth using the included measuring cup or dosage syringe. Before each usage, give the bottle a good shake.
Store in a cool, dry location away from direct sunlight.
6-MP’s Negative Effects
Nausea
Vomiting
Red blood cell count is low.
Appetitelessness
Diarrhea
The mouth is inflamed.
Drug Cautions
Please inform your doctor if you are allergic to Mercaptopurine or any other medications. If you’re pregnant or breastfeeding, avoid Mercaptopurine and talk to your doctor. To avoid pregnancy, it is recommended that you use effective contraception while taking Mercaptopurine and for 3 months after finishing the course. Mercaptopurine should be taken with caution in children, particularly those under the age of six or those with a low BMI, as it can produce low blood sugar. Mercaptopurine may make you more susceptible to illnesses. As a result, if you detect any infection symptoms such as urinary issues, sore throat, or mouth, see your doctor. Mercaptopurine may cause sensitivity to sunlight, thus avoid excessive sun exposure. When going out, it is recommended that you use a high-factor sunscreen and wear protective gear. Mercaptopurine may raise the risk of macrophage activation syndrome (overactivation of white blood cells associated with inflammation), a dangerous illness that affects persons with arthritis. If you’re getting a vaccination, tell your doctor you’re taking Mercaptopurine because it can cause infections.
Interactions between drugs
Mercaptopurine may interact with gout medications (thiopurinol, febuxostat, oxipurinol, allopurinol), anti-inflammatory treatments (mesalazine, sulfasalazine, olsalazine), blood thinners (warfarin, acenocoumarol), infliximab, anticonvulsants (phenytoin, carbamazepine (ribavirin).
No drug-food interactions were discovered.
Before taking Mercaptopurine, tell your doctor if you have TPMT (thiopurine methyltransferase) deficiency, an inherited mutation in the NUDT15-gene (a gene involved in the breakdown of mercaptopurine in the body), Lesch-Nyhan syndrome (a genetic condition), shingles, chickenpox, hepatitis B infection, kidney or liver problems.
Safety Recommendations
Alcohol
Mercaptopurine has no recognized interactions with alcohol. Before drinking alcohol while taking Mercaptopurine, talk to your doctor.
Pregnancy
Mercaptopurine is a category D pregnancy medicine that should not be used during pregnancy, especially during the first three months, because it could harm the fetus. If you are pregnant or planning to become pregnant, please seek medical advice.
Breastfeeding
Mercaptopurine is not recommended for women who are breastfeeding. If you are breastfeeding, please seek medical advice.
Driving
Mercaptopurine does not normally impair your ability to drive or operate machines.
Liver
Mercaptopurine should be used with caution, especially if you have a history of liver illness. Your doctor may alter the dose if necessary.
Kidney
Mercaptopurine should be used with caution, especially if you have a history of kidney illness. Your doctor may alter the dose if necessary.
No habit formation
Advice on Diet and Lifestyle
Maintain a healthy diet that includes nutrient-dense fruits and vegetables, as well as low-fat foods like lean meats, fish, and chicken.
While using Mercaptopurine, drink plenty of water because several cancer treatments might cause dehydration.
Maintain a healthy body weight by exercising regularly.
Wash your hands frequently and avoid contact with those who are sick.
Stop smoking.
Special Instructions
While taking Mercaptopurine, regular blood and urine tests are required to evaluate the quantity of red blood cells, platelets, white blood cells, uric acid levels, and kidney or liver function.
While using Mercaptopurine, do not get any vaccinations unless your doctor has given you permission.
Additional Information : This item cannot be returned.
Concerns of Patients
Blood cancer, often known as leukemia, is a malignancy of the blood cells. It causes the bone marrow to produce an excessive amount of immature white blood cells. Unintentional weight loss, weakness, excessive perspiration, exhaustion, bone pain, repeated infections, chills or fever, red spots on the skin, or painless, swollen lymph nodes, particularly in the armpits and neck, are some of the symptoms. Smoking, genetic or blood problems, a family history of leukemia, heavy radiation exposure, or previous cancer treatment with radiation or chemotherapy are all risk factors for leukemia.
FAQs
6-MP includes Mercaptopurine, which inhibits the formation of genetic material (DNA and RNA) in cancer cells, which is required for cell development, repair, and reproduction. Mercaptopurine prevents aberrant cells from multiplying, causing imbalanced cell growth and cell death.
Mercaptopurine has the potential to harm eggs or induce a low sperm count. If you are going to become a parent, please visit a doctor before taking Mercaptopurine.
6-MP could make you more sensitive to sunlight and UV light. As a result, avoid or minimize prolonged exposure to the sun or artificial light such as tanning beds. Before going out in the sun, wear protective gear and apply sunscreen.
6-MP can cause low blood sugar in children under the age of six and those who are underweight. As a result, take 6-MP with caution in youngsters, and get medical help right away if you experience any symptoms like dizziness, excessive sweating, confusion, or nausea.
If you are about to receive any vaccinations, especially live vaccines like the measles vaccine, flu vaccine, or BCG vaccine, tell your doctor that you are taking 6-MP because it can cause infections.
6-MP has been linked to an increased risk of infection. As a result, if you experience symptoms of infection such as urinary problems, chills, fever, cough, sore throat, or mouth, check your doctor, and avoid contact with persons who have a cold, flu, or illness.
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