About Augmentin 375
Augmentin 375 belongs to a group of antibiotics known as penicillin combination. It is a broad-spectrum antibiotic that works against various types of bacteria. Augmentin 375 is made up of two medicines: Amoxicillin (the active part of antibiotic) and Clavulanic acid (that boosts the efficacy of the amoxicillin). Augmentin 375 is generally prescribed to prevent middle ear and sinus infections, throat or lung respiratory tract infections, urinary tract infections, skin infections, soft tissue infections, dental infections, joint and bone infections.
Augmentin is a combination of Amoxicillin and Clavulanic acid.
Infectious or harmful bacteria can make you sick and reproduce quickly in your body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. Amoxicillin acts by destroying the outer protein layer, thereby killing the bacteria (bactericidal). Clavulanic acid inhibits the enzyme beta-lactamase that prevents bacteria from destroying the efficacy of amoxicillin. As a result, the action of Clavulanic acid allows Amoxicillin to work better and kill the bacteria. Augmentin 375 does not work against infections caused by viruses, including cold and flu.
Augmentin 375 should be taken as prescribed by your doctor, preferably with a meal to avoid stomach upset and at fixed intervals every day for best results. The dose of Augmentin 375 can vary depending upon your condition and the severity of the infection. Also, it is recommended to complete the course of medicine even if you feel better as it is an antibiotic, and leaving it in between may lead to even severe infection that will, in fact, stop responding to the antibiotic as well (antibiotic resistance). The common side effects of Augmentin 375 include vomiting, nausea, and diarrhea. Everyone need not experience the above side effects. In case of any discomfort, speak with a doctor.
Before starting Augmentin 375 , please inform your doctor if you have any allergy (against any antibiotic), kidney or liver problems. Do not take Augmentin 375 on your own as self-medication may lead to antibiotic resistance in which antibiotics fail to act against specific bacterial infections.
Uses of Augmentin 375
Bacterial Infections (Ear infections (acute otitis media), Bronchitis, Pneumonia, Urinary tract infections, skin infections, etc.)
Medicinal Benefits
Augmentin 375 is a broad-spectrum antibiotic that covers a very wide range of bacterial infections. Augmentin 375 has the advantage of having Clavulanic acid, which protects amoxicillin from getting destroyed by the bacterial enzyme increasing its efficacy. Besides this, it helps overcome antibiotic resistance in bacteria caused by the enzyme which destroys amoxicillin (beta-lactamase). This makes the drug effective in multiple infections like ear infections (acute otitis media), bronchitis, pneumonia, urinary tract infections, skin infections, etc. It can be used safely in children, pregnancy, and breastfeeding if taken at the prescription of the doctor.
Directions for Use
Swallow the tablet whole with a glass of water at the start of a meal or slightly before. Space the doses evenly during the day, as prescribed by your doctor. Do not chew or crush it. If you cannot swallow the tablet as a whole, you may break the pill into half and take both halves one at a time.
Storage
Store in a cool and dry place away from sunlight
Side Effects of Augmentin 375
Most of the side effects of Augmentin 375 do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. Some common side effects of Augmentin 375 are vomiting, diarrhea, indigestion, etc. Some people may be allergic to the penicillin group of antibiotics. So a ‘sensitivity test’ may be required before use. Inform your doctor if you are allergic to any antibiotic or the penicillin group of antibiotics in particular. Everyone doesn’t need to experience the above side effects. In case of any discomfort, speak with your doctor.
In-Depth Precautions and Warning
After taking Augmentin 375 , if you have an allergy-like symptom, including rash, swelling of the face/lips/throat, difficulty in breathing, or tightness in the chest, immediately contact your doctor. Do not take Augmentin 375 if you have an allergy to Augmentin 375 , penicillin or cephalosporin class of antibiotics as it may cause skin rash, itching, and difficulty in breathing. People having a liver disease or jaundice (yellowing of skin/eye) should not take Augmentin 375 , as it can damage your liver severely. You may have diarrhea in some cases, which can be managed by taking it with any probiotics and plenty of fluids.
Drug Interactions
Drug-Drug Interaction: Care should be exercised when Amoxicillin and Clavulanic is administered in combination with gout medicine (allopurinol, probenecid), blood thinner (warfarin), anticancer, or anti-arthritis drug (methotrexate), and drug to prevent organ transplant (mycophenolate mofetil).
Drug-Food Interaction: Avoid taking eating high-fat meal as this make harder for your body to absorb Amoxicillin and Clavulanic .
Drug-Disease Interaction: People affected with liver disease (like jaundice), glandular fever (viral infection with fever and sore throat), colitis (bowel disease that affects the large intestine, causing irritation, inflammation, and ulcers in the colon) should not take Amoxicillin and Clavulanic .
Safety Warning
ALCOHOL
It is advisable to avoid the consumption of alcohol during the treatment with Augmentin Tablet, as it may worsen the side effects like dizziness and fits.
PREGNANCY
During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.
BREAST FEEDING
This medication passes into breast milk. Consult your doctor before breast-feeding.
DRIVING
Amoxicillin and Clavulanic may cause dizziness in some people, so it may affect your ability to drive.
LIVER
Amoxicillin and Clavulanic to be taken with caution, especially if you have a history of liver diseases/conditions. Dose may have to be adjusted by your doctor.
KIDNEY
Amoxicillin and Clavulanic to be taken with caution, especially if you have a history of kidney diseases/conditions. Dose may have to be adjusted by your doctor.
Habit Forming: No
Diet & Lifestyle Advise
Probiotics should be taken after taking a full course of Amoxicillin and Clavulanic in order to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhea. Certain fermented foods like yogurt, cheese, sauerkraut, kombucha, and kimchi can help restore the intestine’s good bacteria.
Include more fiber enriched food in your diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fiber rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains like whole-grain bread, brown rice should be included in your diet.
Avoid alcoholic beverages with Amoxicillin and Clavulanic as it can make you dehydrated and may affect your sleep. This can make it harder for your body to aid the Amoxicillin and Clavulanic in fighting off infections.
Special Advise
Amoxicillin and Clavulanic is preferably taken with meals as it can lead to stomach upset. Drink it with a full glass of water.
To prevent throat irritation, take Amoxicillin and Clavulanic in an upright position. Do not lie down for at least 30 minutes of taking it.
Even if you feel better after taking Amoxicillin and Clavulanic , do not stop taking it until your doctor says so. This might cause the symptoms to reappear and make the infection difficult to treat due to antibiotic resistance.
Make sure you drink plenty of fluids when you are sick. This will, in general, help you clear out the infection faster, protect you from dehydration, and help you overcome some unpleasant side effects of taking Amoxicillin and Clavulanic .
Some people may be allergic to Amoxicillin and Clavulanic or other penicillin or cephalosporin group of antibiotics. So a prior sensitivity test may be necessary. Inform your doctor if you are allergic to any medicine, particularly antibiotics belong to these groups.
If you feel nauseous after taking Amoxicillin and Clavulanic , stick to simple meals like porridge, khichdi, dal roti, and other home-cooked meals. Avoid spicy and fatty food.
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Disease/Condition Glossary
Bacterial infection is a condition in which harmful bacteria enter, multiply and infect the body. It can target any part of the body and multiply very quickly. Bacterial infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis. When you get infected with bacteria, you can experience generalized symptoms like fevers, chills, and fatigue. Few harmful bacteria that commonly cause infections include Streptococcus, Staphylococcus, and E. coli. Anyone can get a bacterial infection, but people with a weak immune system or taking immunosuppressive medicines like steroids are more prone to infections.
FAQs
Amoxicillin and Clavulanic is not known to reduce the efficacy of birth control pills and emergency contraceptive pills. However, if you develop diarrhea or vomiting due to Amoxicillin and Clavulanic , you are recommended to use other contraceptive methods such as condoms along with contraceptives to avoid unwanted pregnancies. Discuss with your doctor if you have any concerns regarding the use of Amoxicillin and Clavulanic and your birth control pills.
You need to complete the full course even if you start to feel better to prevent return of infection and resistance to Amoxicillin and Clavulanic .
Amoxicillin and Clavulanic is known to cause stomach upset, indigestion, nausea and diarrhea. To avoid these side effects please take Amoxicillin and Clavulanic with a meal. Also, Amoxicillin and Clavulanic should be taken at evenly spaced intervals to avoid any unpleasant side effects and for best results.
Generally, penicillin group of antibiotics are not advised to be taken with methotrexate which is used for conditions like psoriasis, rheumatoid arthritis etc as they may cause some unpleasant side effects when taken together. However, Amoxicillin and Clavulanic is relatively safer to take with methotrexate but only if prescribed of the doctor. It is best to discuss with your doctor about the use of the two medicines together who may weigh the pros and cons and decide what is best for you.
Usually Amoxicillin and Clavulanic does not cause jaundice. But sometimes, it can cause jaundice in elderly people who have been taking Amoxicillin and Clavulanic for a prolonged time. Please consult your doctor immediately if yellowing of skin/eyes increases.
Amoxicillin and Clavulanic does not treat a viral infection like the flu or a common cold. It is best to consult the doctor to know if you need Amoxicillin and Clavulanic for your condition.
After taking Amoxicillin and Clavulanic , you may have diarrhea. So, drink plenty of fluids and take probiotics to prevent excessive loss of fluids from the body (dehydration). Do not take anti-diarrhea medicine on your own, consult your doctor if the condition worsen.
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