Pazom D
Pazom D is a dopamine antagonist medicine that is used to treat nausea (feeling sick) and vomiting (being sick) in adults and adolescents aged 12 and up. Additionally, it aids in the treatment of dyspepsia. Nausea and vomiting are symptoms of a variety of disorders, including infections, motion sickness, early pregnancy, and gastroparesis (slow stomach emptying).
By inhibiting specific receptors (such as dopamine and serotonin) that stimulate the vomiting center (chemoreceptor trigger zone – CTZ) in the brain, Pazom D decreases nausea and vomiting symptoms. It also functions as a prokinetic agent, increasing the motility of the upper gastrointestinal system and reducing the time it takes for the stomach to empty.
Pazom D should be used before meals because after meals, the medicine’s absorption is slightly delayed. Nausea and vomiting symptoms normally go away 3-4 days after using Pazom D. If the problem persists, discontinue use of this medication and consult a doctor. Pazom D should not be used for more than seven days. Pazom D’s most prevalent side effect is dry mouth. These side effects are usually brief and go away after a while; however, if they persist, consult your doctor. Caffeine-containing beverages (coffee, tea), spicy/deep fried/processed foods, carbonated beverages, and acidic foods (citrus fruits/vegetables) should all be avoided (tomatoes). If you have liver or kidney problems, talk to your doctor before using Pazom D. (kidney function impairment or failure).
Pazom D consumption over an extended period of time has been linked to an elevated risk of heart rhythm disturbance (arrhythmia) and cardiac arrest (heart attack). The elderly (those over 60 years old) and those taking doses greater than 30 mg per day may be at higher risk. If you’re on antifungal medication or have cardiac problems or AIDS/HIV, tell your doctor. If you suffer heart rhythm problems such as palpitations, difficulty breathing, or loss of consciousness after taking Pazom D, call your doctor right once. Pazom D should not be given to adolescents (children aged 12 to 18) who weigh less than 35 kg.
Pazom D’s Applications
Nausea and vomiting can both be prevented.
Medicinal Advantages
Pazom D includes domperidone, a dopamine antagonist that works by inhibiting certain brain receptors that cause vomiting. Pazom D also functions as a prokinetic agent, increasing the motility of the upper gastrointestinal system and shortening the time it takes for food to leave the stomach.
Use Instructions
Pazom D should be taken 15-30 minutes before a meal. Pazom D should be taken with a glass of water and drunk whole. It should not be chewed, crushed, or broken. Pazom D is now available in a liquid version for those who are unable to take tablets or capsules. Pazom D should not be used for longer than 7 days.
Store in a cool, dry location away from direct sunlight.
Pazom D Side Effects
Every drug has its own set of adverse effects. Pazom D, too, has a common adverse effect of dry mouth. This is a transitory side effect that may go away after some time; however, if it persists, consult your doctor.
Drug Recommendations
Domperidone use for a long time has been linked to an elevated risk of heart rhythm problem (arrhythmia) and cardiac arrest (heart attack). The elderly (those over 60 years old) and those taking doses greater than 30 mg per day may be at higher risk. If you’re on antifungal medication or have cardiac problems or AIDS/HIV, tell your doctor. If you suffer heart rhythm problems such as palpitations, difficulty breathing, or loss of consciousness after taking Domperidone, call your doctor right once. Domperidone should not be administered to adolescents (children aged 12 to 18) who weigh less than 35 kg.
Interactions Between Drugs
Drug-drug interactions:Domperidone should not be taken with medicines for heart problems or high blood pressure (amiodarone, dronedarone, quinidine, disopyramide, dofetilide, sotalol, diltiazem, verapamil), depression (citalopram, escitalopram), anti cancer agents (toremifene, vandetanib, vincamine), bacterial infections (specifically erythromycin, clar
Interactions with Grapefruit Juice, Alcohol, and Cigarettes: Domperidone may interact with grapefruit juice, alcohol, and tobacco. Domperidone’s efficacy may be impaired as a result of this. As a result, Domperidone should not be taken with them.
Drug-Disease Interaction: Domperidone should not be used by those who have liver disease, brain tumors, a history of gastrointestinal bleeding, or any other bowel condition.
Safety Suggestions
ALCOHOL
When Domperidone is combined with alcohol, it can produce drowsiness or an irregular heartbeat.
PREGNANCY
Domperidone is generally not advised during pregnancy.
BREAST FEEDING
Domperidone is not normally advised to be taken during nursing because it only passes through the breast milk in modest doses. Consult a physician since other medications may be more effective.
DRIVING
Domperidone can make you sleepy and confused, so you should avoid operating machinery or driving a car because it can impair your ability to concentrate.
LIVER
In patients with liver illness, Domperidone should be used with caution.
KIDNEY
In patients with kidney issues, domperidone should be used with caution. Depending on the state of your ailment, your doctor will change your dose.
No habit formation
Advice on Diet and Lifestyle
Eat a nutritious, low-fat diet, especially in little servings, as this will make digestion easier. If you’ve been vomiting, limit your intake of sweet foods and increase your intake of salty foods.
Also, if you enjoy vomiting at a certain time of day, avoid eating your favorite meal at that time, as your taste for it may be turned off.
Clear soups, flavored gelatin, and carbonated beverages are examples of cool beverages to include in your diet. Also, sip gently when drinking with a stray to prevent swallowing air, which can cause gas or acidity.
After eating, drink water or any other liquid for at least 30 minutes. After eating, lay down for at least 2 hours.
If the scent of food makes you sick (vomit), don’t cook it because it could make your condition worse. Allow someone else to make the food or utilize frozen prepared foods.
Other details: This item is non-refundable.
Concerns of Patients
Nausea is an uneasiness in the stomach that often precedes vomiting. Vomiting, on the other hand, is the forced or involuntary emptying of the stomach contents through the mouth. In short, nausea and vomiting are symptoms of a variety of disorders, including infections, motion sickness, early pregnancy, and gastroparesis (slow stomach emptying). Vomiting is controlled by a receptor in our brain called the chemo receptor zone (CTZ).
FAQs
Domperidone may cause sleepiness and make it difficult to concentrate, so do not drive or ride a bike while taking it. So, if you’re dizzy, don’t get behind the wheel.
If you have a sugar intolerance, tell your doctor before starting Domperidone because it contains lactose. So, to avoid any unpleasant side effects, follow your doctor’s instructions.
Dry mouth is a side effect of Domperidone. If you’re feeling very thirsty, drink more water and rinse your mouth frequently.
If you forget to take a dose, take it as soon as you remember. If your next dose is approaching, wait until it is due and then proceed as usual. To make up for a missed dose, do not take a double dose.
Contact your doctor or the nearest hospital casualty department if you or someone else has taken too much Domperidone.
Alcohol should be avoided when taking Domperidone since it can exacerbate adverse effects such as tiredness or an irregular heartbeat.
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