ZOLDONAT 4MG Injection 1 vial

ZOLDONAT 4mg

ZOLDONAT 4MG is a bisphosphonate, a type of drug used to treat osteoporosis (weak, brittle bones) caused by menopause or long-term steroid usage. Paget’s disease and cancer-related elevated calcium levels are also treated with ZOLDONAT 4MG. Osteoporosis is a bone disease that weakens and thins bones by lowering bone density. It is more frequent in women after menopause. Bones become weaker and more likely to break when their density falls.

ZOLDONAT 4MG includes Zoledronic acid, which binds to the bone securely and prevents osteoclasts from removing calcium (a type of bone cells that destroy bone tissue). This keeps the bones healthy and reduces the chance of their breaking by preventing osteoclasts from breaking them down.

ZOLDONAT 4MG is administered intravenously by a doctor or nurse (IV). You should take ZOLDONAT 4MG as directed by your doctor for as long as your medical condition requires it. Headache, fever, nausea, dizziness, vomiting, back pain, diarrhea, discomfort in the muscles, joints, or bones, edema, or pain at the infusion site are all possible side effects. The majority of these ZOLDONAT 4MG side effects do not require medical care and will go away over time. Please visit your doctor if the side effects persist or worsen.

Please inform your doctor if you are allergic to ZOLDONAT 4MG or any other medications. If you are pregnant or breastfeeding, check your doctor before using ZOLDONAT 4MG. Because the safety and effectiveness of ZOLDONAT 4MG have not been proved, it is not recommended for children under the age of 18. If you have hypocalcemia (low calcium levels in the blood) or severe kidney problems, don’t use ZOLDONAT 4MG. Because ZOLDONAT 4MG can produce dizziness, you should only drive if you are attentive. In some people, ZOLDONAT 4MG may induce osteonecrosis of the jaw (ONJ). Consult your doctor and dentist if you have any problems with your teeth or mouth, such as loose teeth, swelling or pain, non-healing sores, or discharge, as these could be indicators of osteonecrosis of the jaw.

ZOLDONAT 4MG’s Applications

Postmenopausal osteoporosis, Paget’s disease, and cancer-related hypercalcemia (high calcium levels)

Medicinal Advantages

ZOLDONAT 4MG is a drug that contains Zoledronic acid, which is used to treat postmenopausal osteoporosis, Paget’s disease, and malignancy-related hypercalcemia (bone cancer in which excess of calcium exits). ZOLDONAT 4MG adheres to the bone securely and stops osteoclasts from removing calcium (a type of bone cells that destroy bone tissue). This stops osteoclasts from breaking down the bone, so strengthening it and reducing the chance of fracture. ZOLDONAT 4MG may also lower blood calcium levels by limiting calcium reabsorption from the bones into the blood. As a result, it aids in the treatment of cancer-related elevated calcium levels in the blood.

Use Instructions

A doctor or nurse administers ZOLDONAT 4MG as an intravenous (into a vein) infusion. Do not self-medicate.

Storage

Store in a cool, dry location away from direct sunlight.

ZOLDONAT 4MG Side Effects

Headache

Fever

Nausea

Dizziness

Vomiting

Back ache

Diarrhea

Symptoms of the flu (chills, tiredness, muscle and joint pain)

Muscle, joint, or bone pain is a common complaint.

Swelling or soreness at the site of the infusion

Drug Recommendations

Please inform your doctor if you are allergic to ZOLEDRONIC ACID or any other medications. If you are pregnant or breastfeeding, check your doctor before using ZOLEDRONIC ACID. Because the safety and effectiveness of ZOLEDRONIC ACID have not been proved, it is not recommended for children under the age of 18. If you have hypocalcemia (low calcium levels in the blood) or severe kidney problems, you should avoid using ZOLEDRONIC ACID. Because ZOLEDRONIC ACID might cause dizziness, you should only drive if you are attentive. Before taking ZOLEDRONIC ACID, tell your doctor if you are unable to take daily calcium supplements, if you have had sections of your intestine or some or all of your parathyroid glands surgically removed, if you have cancer, gum disease, poor dental health, or planned tooth extraction, or if you have a kidney problem. If you smoke, tell your doctor before using ZOLEDRONIC ACID because it could make you more susceptible to tooth problems. In some cases, ZOLEDRONIC ACID might induce osteonecrosis of the jaw (ONJ). Consult your doctor and dentist if you have any problems with your teeth or mouth, such as loose teeth, swelling or pain, non-healing sores, or discharge, as these could be indicators of osteonecrosis of the jaw. To avoid dehydration, drink at least 2 glasses of fluids before and after treatment with ZOLEDRONIC ACID, as directed by your doctor. Because ZOLEDRONIC ACID may lower calcium levels in the blood, you should take calcium and vitamin D supplements as directed by your doctor.

Interactions Between Drugs

Antibiotics (gentamicin) and water tablets may have an interaction with ZOLEDRONIC ACID (furosemide).

No drug-food interactions have been discovered.

If you have hypocalcemia (low calcium levels in the blood) and severe kidney problems, you should avoid taking ZOLEDRONIC ACID. Before taking ZOLEDRONIC ACID, tell your doctor if you have cancer, gum disease, poor dental health, or a planned tooth extraction, or if you have a kidney condition.

Safety Suggestions

ALCOHOL

Alcohol’s interaction with ZOLEDRONIC ACID is unknown. Before consuming alcohol while taking ZOLEDRONIC ACID, please check your doctor.

PREGNANCY

ZOLEDRONIC ACID is a category D pregnancy medicine that should not be used by pregnant women due to the risk of harming the unborn child. If you are pregnant, please seek medical advice.

BREAST FEEDING

ZOLEDRONIC ACID is not recommended for moms who are breastfeeding. If you are breastfeeding, please seek medical advice.

DRIVING

DRIVING WITH ZOLEDRONIC ACID can make you dizzy. As a result, if you feel dizzy after taking ZOLEDRONIC ACID, don’t drive or operate machinery.

LIVER

If you have a history of liver disease or condition, use ZOLEDRONIC ACID with caution. Your doctor may alter the dose if necessary.

KIDNEY

If you have a history of kidney illness or condition, use ZOLEDRONIC ACID with caution. Your doctor may alter the dose if necessary. If you have serious kidney problems, you should avoid taking ZOLEDRONIC ACID.

No habit formation

Advice on Diet and Lifestyle

Include dairy items in your diet, such as milk, yoghurt, cheese, and milk-based custard.

Broccoli, cabbage, bok choy (Chinese white cabbage), spinach, and other green leafy vegetables should be consumed on a daily basis.

Snacking on calcium-rich nuts such as Brazil nuts or almonds is a good idea.

Sesame seeds can be sprinkled on food, vegetables, and salads. Calcium is abundant in sesame seeds.

Caffeine, soft drinks, and alcohol, all of which impede calcium absorption, should be avoided or limited.

To get more calcium in your diet, swap out the beef for tofu or tempeh.

Recommendations

Before using ZOLEDRONIC ACID, you should get a dental checkup because it has been linked to jaw osteonecrosis.

To monitor kidney function, a blood test is recommended before each dose of ZOLEDRONIC ACID.

While on ZOLEDRONIC ACID therapy, your doctor may urge that you consume calcium and vitamin D on a regular basis.

You may have musculoskeletal pain when using ZOLEDRONIC ACID; in this event, discontinue taking ZOLEDRONIC ACID and visit a doctor.

Additional Information: This item is non-refundable.

Concerns of Patients

Osteoporosis is a bone disease that causes bones to weaken and thin by lowering bone density. Bones become weaker and more likely to break when their density falls. Because women’s ovaries stop generating estrogen (a female hormone) necessary for bone health at menopause, postmenopausal women are more prone than males to develop osteoporosis. Bone loss happens after menopause, making bones fragile and more likely to shatter. Long-term steroid use can also weaken bones and cause osteoporosis in both men and women. Back pain from a broken or collapsed vertebra, loss of height over time, a stooped posture, and a bone that breaks much more easily than predicted are all signs and symptoms.

Paget’s disease occurs when bone remodeling (removal of old bone and replacement with new bone material) occurs too quickly, resulting in new bone that is weaker than normal. The bone may grow misshapen, uncomfortable, and break if not addressed.

In some cancers, such as breast cancer, lung cancer, or blood cancer, there is an excessive amount of calcium in the bloodstream. Nausea, vomiting, constipation, headaches, and a loss of appetite are some of the symptoms of a high calcium level.

FAQs

ZOLDONAT 4MG includes Zoledronic acid, which binds to the bone securely and prevents osteoclasts from removing calcium (a type of bone cells that destroy bone tissue). This keeps the bones healthy and reduces the chance of their breaking by preventing osteoclasts from breaking them down.

If you have hypocalcemia (low calcium levels in the blood), you should avoid using ZOLEDRONIC ACID since it could make your condition worse. Before initiating treatment with ZOLEDRONIC ACID, however, calcium and vitamin D levels should be tested.

ZOLEDRONIC ACID can lead to osteonecrosis (jaw bone deterioration). Maintain good oral hygiene and have frequent dental check-ups while taking ZOLEDRONIC ACID to avoid this disease. Also, if you use dentures, ensure that they are well fitted. Consult your doctor and dentist if you have any problems with your teeth or mouth, such as loose teeth, swelling or pain, non-healing sores, or discharge, as these could be indicators of osteonecrosis of the jaw.

It is not suggested that you take ZOLEDRONIC ACID with gentamicin because the two medicines together may increase the risk of very low calcium levels in the blood. If you’re using ZOLEDRONIC ACID with other medications, talk to your doctor first.

By limiting calcium reabsorption from the bones into the blood, ZOLEDRONIC ACID may lower calcium levels in the blood. As a result, after getting ZOLEDRONIC ACID, your doctor may prescribe calcium and vitamin D supplements, which you should take for at least 10 days.

As a typical side effect, ZOLEDRONIC ACID might induce flu-like symptoms (chills, weariness, muscular and joint pain) in some patients. Please visit a doctor if the symptoms persist or worsen after two weeks.