ZYCOLCHIN TAB Colchicine 10 Tablets

About Zycolchin  0.5 mg

Zycolchin 0.5 mg is an anti-inflammatory agent and belongs to the class of anti-gout agents. It is used in the treatment and prevention of acute attacks or flare-ups of gout. Gout is a chronic condition that occurs due to the deposition of uric acid crystals in the joints. It is characterized by intense pain and swelling at the affected joints. Zycolchin 0.5 mg decreases the pain, swelling, and inflammation. It also prevents sudden attacks of pain caused by acute gout.

Zycolchin 0.5 mg is usually used as a combination therapy with other drugs to treat gout. It is primarily available for oral use in the form of a tablet or capsule. Do not crush, chew, or break the tablet. Swallow it as a whole with a glass of water. You may experience side-effects such as diarrhea, nausea, and vomiting. These effects gradually resolve over time. However, if the side-effects persist, consult your doctor.

Inform your doctor if you are allergic to Zycolchin 0.5 mg or any other medicines. Pregnant and breastfeeding women should use Zycolchin 0.5 mg with proper consultation and caution. Do not take Zycolchin 0.5 mg if you have severe blood disorder, kidney or liver problems and you are taking certain medicines. Do not stop taking Zycolchin 0.5 mg even if there is no pain. Complete the course of the treatment as prescribed by the doctor. Seek medical attention immediately if you observe any abnormal signs or symptoms.

Uses of Zycolchin 0.5 mg:   Treatment of acute gout, prevention of gout attacks

Medicinal Benefits

Zycolchin 0.5 mg has anti-inflammatory properties. It works by targeting white blood cells (neutrophils). It reduces the inflammation caused by uric acid crystals in the affected joints, thereby reducing pain, swelling, and inflammation.

Directions for Use

Zycolchin 0.5 mg should not be used unless prescribed by a doctor. The doctor will prescribe the required dose and duration depending on the severity of your disease. Take this tablet as a whole with a glass of water. You can take this medicine with or without food.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Zycolchin 0.5 mg

Gastrointestinal effects such as nausea, vomiting, diarrhea, and abdominal pain are common side-effects of Zycolchin 0.5 mg. Fatigue and headache are also seen in some patients. Other less common side-effects are muscle pain, weakness, hair loss, rash, loss of appetite, and male infertility (low sperm production). These side-effects gradually resolve over time. If the condition worsens or there are any abnormal signs, seek medical help immediately.

Drug Warnings

Zycolchin 0.5 mg should not be used in patients with liver diseases as it increases the risk of muscle damage. It should be used with caution in patients with kidney problems and blood disorders. Pregnant women, breastfeeding mothers, and children below 12 years should use only with a doctor’s advice. Overdose of Zycolchin 0.5 mg may lead to abdominal pain, severe nausea, bloody stools, and dizziness.

Drug Interactions

Drug-drug interactions: Zycolchin 0.5 mg may interact with lipid-lowering medications such as atorvastatin and rosuvastatin, medicine used to treat heart disorders such as digoxin, nonsteroidal anti-inflammatory drugs (NSAIDs) such as naproxen and ibuprofen, anti-fungal drugs such as ketoconazole and itraconazole, drugs used to treat alcoholism such as disulfiram, antibiotics such as clarithromycin, and antidepressants such as nefazodone. 

Drug-food interactions: Intake of alcohol may increase the risk of side-effects. So, avoid taking alcohol with Zycolchin 0.5 mg.  Avoid eating grapefruit or grapefruit juice as it may also increase the risk of serious side-effects.

Drug-disease interactions: Patients with blood disorders such as blood dyscrasias (imbalance of white blood cells, red blood cells, or platelets, or impairment in bone marrow function), kidney diseases, liver problems, or heart disorders.

Safety Advice

ALCOHOL

Alcohol may affect Colchicine effectiveness. So, people should avoid taking alcohol while using Zycolchin 0.5 mg.

PREGNANCY

Pregnant women should take Colchicine only when prescribed by a doctor.

BREAST FEEDING

The safe use of Colchicine in breastfeeding mothers has not yet been established. So, it should be used in breastfeeding women only when prescribed by a doctor.

DRIVING

Driving should be avoided as  may cause dizziness.

LIVER

Colchicine may cause liver damage. So, it should be advised with caution in patients with liver diseases.

KIDNEY

Colchicine should be used with caution in patients with renal impairment. The doctor may adjust the dose depending on your condition.

Habit Forming :  No

Diet & Lifestyle Advise

Include more glucosamine, chondroitin sulphate, vitamin D, calcium-enriched supplements. Besides this, turmeric and fish oils can help in reducing inflammation in the tissue.

Do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching, low impact aerobic exercise like walking on a treadmill, bike riding, and swimming. You can also strengthen your muscles by lifting light weights.

Do not take grapefruit or grapefruit juice. And avoid the intake of alcohol.

In chronic conditions of arthritis or joint pain, fish like salmon, trout, tuna, and sardines. These fishes are enriched with omega-3 fatty acids that minimize chemical cytokines, which ramp up inflammation.

Your sitting posture is important, especially when you have pain and inflammation. Try to sit as little as possible, and only for a short duration of time. Long term immobility is harmful in conditions like arthritis.  Use back support like a rolled-up towel at the back of your spine curve to minimize pain. Keep your knees and hips at a right angle. Besides this, you can also use a footrest if required.

Other Information:  This item is Not Returnable.

Disease/Condition Glossary

Gout is a type of arthritis in which patients experience severe pain, redness, and swelling in joints. The most common affected area is the joint at the base of the big toe. It occurs due to a condition called hyperuricemia (high uric acid levels in the body). The excess uric acid deposit and crystallize in the joints leading to pain and inflammation. Patients with gout may often experience acute attacks that result in sudden and severe pain.

FAQs

Do not take the missed dose and take the next dose at the fixed time.

Colchicine is the first-line therapy for gout. It can be used along with Colchicine as there are no interactions between the two drugs. However, it is recommended to take the medicine after consulting a doctor.

Colchicine may lower blood pressure and make you feel light-headed or dizzy.

Colchicine treats gout by acting white blood cells. Therefore, it may show an effect on the immune system. Consult your doctor before stopping any medicine, don’t stop your medication suddenly.