Glimisave M 2
Glimisave M 2 contains two anti-diabetic medications: Glimepiride and Metformin. Glimepiride is a’sulfonylurea’ medication that works by boosting the amount of insulin produced by the pancreas. Metformin, a ‘biguanide,’ works by decreasing the amount of glucose produced in the liver, delaying the absorption of glucose from the intestines, and enhancing the body’s sensitivity to insulin. In a nutshell, the two medications work in tandem to prevent blood glucose levels from climbing to dangerously high levels, hence maintaining control of your Diabetes.
Type 2 diabetes is a chronic or lifelong disease that impairs your body’s glucose metabolism. Type 2 diabetes patients either do not create enough insulin or produce insulin that is unable to accomplish its role in the body (insulin resistance). This results in a rise in blood glucose and the onset of symptoms such as frequent urination, increased thirst, and increased hunger. It can result in serious complications such as skin infection, eye difficulties (retinopathy), nerve damage (neuropathy), diabetic foot (foot ulcer), kidney disease (nephropathy), hypertension (hypertension), and even stroke.
The two medications in Glimisave M 2 work in concert to keep your blood sugar levels in balance using the methods mentioned above. Strict blood sugar control is critical, especially in light of the numerous severe complications of Diabetes. Glimisave M 2 produces the best results when combined with healthy lifestyle modifications such as weight loss, frequent exercise, and a balanced diet.
To avoid an upset stomach, Glimisave M 2 should be taken with food. Glimisave M 2 should be taken consistently at the same time of day. To ensure the best possible care, your doctor will determine the appropriate dose, which may change periodically based on your health. Hypoglycemia (low blood glucose levels) is a typical adverse effect of Glimisave M 2. Symptoms include dizziness, sweating, palpitations, hunger pangs, and dry mouth and skin. Therefore, to avoid hypoglycemia, you should avoid skipping meals and carry some form of sugar with you. Additionally, taste changes, nausea, diarrhoea, stomach pain, headache, and upper respiratory symptoms may occur.
Even if you feel better, do not stop taking Glimisave M 2 without visiting your doctor, as your blood sugar level will continue to fluctuate. If you suddenly stop using Glimisave M 2, your blood sugar levels may rise, increasing your risk of vision loss (retinopathy), kidney problems (nephropathy), and nerve damage (neuropathy). If you have type 1 diabetes mellitus, severe renal or liver illness, you should not take Glimisave M 2. Kindly inform your doctor if you have a cardiac condition, are pregnant or planning to become pregnant, or are breastfeeding.
Glimisave M 2 Diabetes Mellitus Type 2 Indications
Medicinal Advantages
Glimisave M 2 aids in blood sugar regulation without causing weight gain. Additionally, it is cardioprotective, avoiding future cardiac issues. Additionally, Glimisave M 2 aids in the prevention of significant diabetes consequences such as kidney damage (Diabetic Nephropathy), blindness (Diabetic Retinopathy), loss of sensation in the hands and feet (Diabetic Neuropathy), and even foot amputation! Additionally, Glimisave M 2 helps to lower your risk of suffering a heart attack or stroke. Due to the fact that it is a mixture of two medications, it eliminates the need to take several pills and so makes it easier to remember to take the medications.
Use Instructions
Take Glimisave M 2 as directed by your physician. Take it with food to avoid stomach distress. Consume it in its entirety with a glass of water. Avoid chewing or crushing it. If you miss a dosage of Glimisave M 2, do not increase the dose as this may result in a dangerously low blood sugar level (hypoglycemia).
Storage Keep out of direct sunlight and in a cool, dry area.
Glimisave M 2 Adverse Reactions
The majority of Glimisave M 2’s negative effects are mild and resolve on its own. However, if the adverse effects persist, consult your physician. Hypoglycemia (low blood glucose level) is a typical adverse effect of Glimisave M 2. Symptoms include dizziness, sweating, palpitations, hunger pangs, and dry mouth and skin. Additionally, some individuals may have changes in their taste, nausea, diarrhea, stomach pain, flatulence, headache, upper respiratory symptoms, and skin rash. Not everyone will experience the above-mentioned adverse effects. Consult your physician if you have any discomfort.
Adverse Drug Reactions
Certain diabetic patients using Glimepride and Metformin may develop a potentially fatal condition known as lactic acidosis. Lactic acidosis occurs when an abnormal amount of lactic acid accumulates in the blood. Thus, normal functioning of the liver and kidneys is essential for the clearance of excess lactic acid from the blood. Metformin should not be used if you have renal disease as determined by a blood test. Because glimepride and metformin may deplete vitamin B12 levels, it is recommended that you get blood and vitamin tests on an annual basis. When used with insulin, metformin has been shown to significantly reduce blood sugar levels. As a result, the doctor may reduce the insulin dose.
Interactions Between Drugs
Glimisave M 2 may interact with insulin, blood pressure-lowering medications (hydrochlorothiazide, amlodipine), water pills/diuretics (furosemide), heart failure medications (digoxin), antihypertensive medications (metoprolol), steroids (prednisolone), and thyroid hormones, among other medications. Therefore, inform your doctor if you are currently taking any of these medications prior to starting Glimepride or Metformin.
Glimisave M 2 may raise the risk of lactic acidosis (a build-up of lactic acid in the blood) and hypoglycemia, which are rare but serious and potentially life-threatening conditions.
Glimepride and Metformin should be avoided in patients with vitamin B12 deficiency, kidney or liver difficulties, cardiovascular illness (heart-related problems), or low blood sugar (hypoglycemia), since they may exacerbate the condition.
Safety Suggestions
ALCOHOL WARNING
If you drink alcohol, you should not take Glimepride or Metformin until prescribed. Combining Glimepride and Metformin with alcohol can result in hypoglycemia and a rare but potentially fatal disease called Lactic Acidosis. Therefore, inform your physician if you consume alcohol.
PREGNANCY
It is not recommended to take Glimepride or Metformin during pregnancy. However, if your doctor believes the benefit to you outweighs the danger, he or she may prescribe it for you during pregnancy. Glimepride with Metformin should not be used without consulting a physician.
BREAST FEEDING
It is not suggested to use this name when breastfeeding. However, if your doctor believes the benefit to you outweighs the risk, he or she may prescribe it for you while nursing. Glimepride with Metformin should not be used without consulting a physician.
DRIVING
Glimepride and Metformin both have the potential to produce hypoglycemia (low blood sugar levels), which is characterized by unusual drowsiness, shivering, palpitations, and excessive perspiration. This may impair your driving skills. Exercise cautious when driving or performing other tasks that need focus.
LIVER
If you have a history of or indications of liver disease, please see your doctor prior to using the medication. Your doctor may need to alter the dose.
KIDNEY
If you have a history of or indications of kidney illness, please see your doctor prior to using the medication. Your doctor may need to alter the dose.
No Habit Formation
Advice on Diet and Lifestyle
Half of your plate should be starchy vegetables, a quarter protein, and a quarter whole grain.
Consume food at regular intervals. Do not wait an extended period of time between meals or snacks.
Regularly monitor your blood sugar level, especially if there are significant swings.
Each week, commit to at least 150 minutes of moderate-intensity physical activity or one hour and 15 minutes of vigorous exercise.
Weight loss should be gradual in order to maintain a healthy body mass index (18.5 to 24.9).
Substitute whole grain foods for refined carbohydrate foods and boost your intake of fruits, vegetables, and other fiber-rich foods.
Reduce saturated fat (or hidden fat) consumption in foods such as chips, crisps, pastries, biscuits, and samosas. For daily cooking, choose oils high in omega 3 fatty acids. Use palm oil, mustard oil, groundnut oil, rice bran oil, or safflower oil for frying.
Avoid stress, as it may cause your blood sugar level to rise. You can control stress-related blood sugar variations by implementing stress management practices such as mindfulness.
Make a point of purchasing low-fat dairy products (low-fat yogurt, fat-free milk, and cheese, etc.).
Maintain a normal blood pressure (140/90) as much as feasible. Due to the fact that it lowers the risk of cardiovascular disease in diabetic people.
Special Guidance
Continue taking the medication even if you believe your blood sugar levels are stable. If you miss a dosage, do not double the dose; instead, visit your medical physician.
When using this medication, consume small frequent meals and prevent prolonged fasting. Be aware of hypoglycemic symptoms such as excessive sweating, dizziness, palpitations, shivering, severe thirst, dry mouth, dry skin, and frequent urination. If you encounter any of the symptoms listed above, immediately ingest 5-6 candies, 3 glucose biscuits, or 3 teaspoons of honey/sugar and see your physician. Keep them with you at all times, especially on lengthy journeys.
It is always preferable if your physician is aware of any underlying illnesses such as renal or liver disease, prior heart attack, or alcohol consumption before prescribing this medication.
Avoid alcohol consumption while taking this medication as it raises the risk of hypoglycemia (a dangerous drop in blood sugar that can be fatal in some situations) and lactic acidosis (when the lactic acid increases in the body which impacts the functioning of various organs in the body).
Quit smoking and limit carbohydrate-rich foods such as potatoes, rice, mangoes, bread, and sugar.
Bear in mind that the most critical step toward controlling blood sugar levels is lifestyle adjustment.
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Concern for Patients
Diabetes Mellitus type 2 is a disorder in which the body either produces insufficient insulin (the hormone that aids in lowering blood sugar levels) or insulin is resistant to its action. As a result, extra insulin is created but does not reach the body’s organs. Type 2 diabetes symptoms include constant exhaustion, thirst, blurred vision, and an increased urge to urinate (pee). Skin infection, vision difficulties (retinopathy), nerve damage (neuropathy), diabetic foot (foot ulcer), kidney disease (nephropathy), high blood pressure, and even stroke are all complications of type 2 diabetes. Both low and high blood sugar levels are potentially harmful and should be handled promptly. Your H1bA1C level should be less than 5.7 percent for normal, 5.7-6.4 percent for prediabetes, and 6.5 percent or above for diabetes.
FAQs
Kind 2 diabetes is a frequent type of diabetes in which the body’s natural blood sugar-lowering hormone, insulin, does not operate effectively. As a result, blood glucose levels rise, and symptoms such as frequent urination, increased thirst, and increased appetite begin to manifest. Diabetes, if left untreated or not adequately treated, can result in long-term complications such as nerve damage, kidney damage, eye damage, and foot difficulties, as well as a significantly increased risk of developing heart disease.
Hypoglycemia is a term that refers to dangerously low blood sugar levels. Glimepride and Metformin both have the potential to cause hypoglycemia. Hypoglycemia symptoms include nausea, headache, irritability, hunger, perspiration, dizziness, rapid heart rate, and a sense of anxiety or shakiness. Hypoglycemia can develop if you skip or delay meals, drink alcohol, over-exercise, or combine this medication with another antidiabetic medication. As a result, it is critical to monitor blood sugar levels on a frequent basis. Diabetes patients are recommended to carry a rapid source of sugar with them, such as glucose tablets, chocolate, glucose biscuits, honey, or fruit juice. If you encounter any of the hypoglycemic symptoms, notify your health care expert, who may then change the medication’s dose to meet your specific needs.
Glimisave M 2 should not be used in people who are allergic to any of the medication’s components or excipients. It is contraindicated in persons with moderate to severe kidney or liver problems. Additionally, it is not recommended to use this medication if you consume an excessive amount of alcohol. If you are pregnant or breastfeeding, inform your health care expert.
Glimisave M 2 may produce a mild stomach upset. However, do not discontinue use. Consult your physician if you experience severe stomach distress.
Weight loss is a documented side effect of initial treatment with Glimepride and Metformin. However, if you have significant weight loss while taking Glimepride and Metformin, contact your doctor immediately. It is possible that your dosage might be modified.
If you have increased thirst after taking Glimepride and Metformin, this could be due to dehydration, as Glimepride and Metformin can promote fluid loss. Increase your fluid intake; if you continue to feel thirsty, visit your doctor.
If you have diabetes, you should undergo a HbA1c test every three months.
If you have increased hunger, increased thirst, frequent urination (typically at night), unexplained weight loss, exhaustion, hazy vision, slow wound/sore healing, or repeated infections, consult a physician as this could be a sign of type 2 diabetes.
If you feel as though your blood sugar is dropping and you are becoming weak, immediately consume sugar candies or sugary beverages. It will assist in balancing your body’s blood sugar levels. As a result, it is prudent to have sugar candies with you.
Lactic acidosis is an uncommon but potentially fatal illness that occurs when the bloodstream accumulates too much lactic acid. When cells are depleted of oxygen, long-term use of Glimepride and Metformin may result in lactic acidosis. Lactic acidosis symptoms include muscle burning, soreness, rapid breathing, nausea, and stomach pain. Lactic acidosis is extremely uncommon while taking Glimepride with Metformin. Contact your physician immediately if you notice this complication.
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