LIPAGLYN 4 MG 10 Tablets

Lipaglyn

Lipaglyn is an insulin sensitizer that is used to treat type-2 diabetes individuals with dyslipidemia/hypertriglyceridemia that is not managed by statins (lipid-lowering medications). Lipaglyn combines lipid- and glucose-lowering properties in a single molecule, assisting in the reduction of blood triglycerides and glucose levels. Diabetic dyslipidemia is defined by elevated triglyceride, low-density lipoproteins (LDL), and decreased high-density lipoproteins (HDL). This is a common complication of type-2 diabetes mellitus.

Lipaglyn includes ‘Saroglitazar,’ a dual PPAR-/-agonist with a significant PPAR-alpha impact and a modest PPAR-gamma effect. PPAR-alpha inhibits triglyceride production and release, but promotes lipolysis and hepatic oxidation of fatty acids. Additionally, it stimulates the creation of HDL cholesterol. PPAR-gamma relieves the liver and muscle of metabolic load and improves glucose consumption. It enhances insulin-mediated post-absorptive reduction of hepatic glucose production. As a result, Lipaglyn contributes to the reduction of blood lipid and glucose levels.

Take Lipaglyn at the same time each day, with or without food. Lipaglyn should be swallowed whole with a glass of water; the tablet should not be broken or chewed. It is recommended that you continue taking Lipaglyn for as long as your doctor prescribes it, based on your medical condition. Certain typical adverse effects may occur in some circumstances, including stomach irritation, nausea, vomiting, weakness, chest discomfort, disorientation, and fever. The majority of these adverse effects are temporary and will resolve on their own. However, it is recommended that you visit your doctor if you continue to suffer any adverse effects.

If you are pregnant, see your doctor before using Lipaglyn. Because it is unknown whether Lipaglyn is secreted in breast milk, breastfeeding mothers should avoid using Lipaglyn. Lipaglyn should not be given to minors due to the lack of documented safety and efficacy. Lipaglyn should be used cautiously in patients with kidney or liver disease, as well as in the elderly. Avoid drinking alcohol while taking Lipaglyn because it may induce unpleasant side effects. Lipaglyn may cause dizziness, therefore exercise caution while driving. Inform your physician of the medications you are currently taking and your current health status to rule out any unwanted side effects.

Lipaglyn is used to treat diabetic dyslipidemia/hypertriglyceridemia.

Medicinal Advantages

Lipaglyn is an insulin sensitizer that is used to treat type-2 diabetes patients with dyslipidemia/hypertriglyceridemia that cannot be managed with statins alone. Lipaglyn has been shown to decrease triglycerides (TG), Low-Density Lipoprotein (LDL) cholesterol, non-High-Density Lipoprotein (non-HDL) cholesterol, and Very Low-Density Lipoprotein (VLDL) cholesterol while increasing HDL cholesterol. It has also been proven to improve glycemic indices in diabetic individuals by reducing fasting plasma glucose and glycosylated hemoglobin. Lipaglyn is a dual Peroxisome Proliferator-Activated Receptor (PPAR) agonist/ antagonist with a significant effect on PPAR-alpha and a modest effect on PPAR-gamma. PPAR-alpha inhibits triglyceride production and release, but promotes lipolysis and hepatic oxidation of fatty acids. Additionally, it stimulates the creation of HDL cholesterol. PPAR-gamma alleviates the metabolic burden on the liver and muscle, stimulates glucose utilization, and enhances insulin-mediated post-absorptive reduction of hepatic glucose production. Lipaglyn combines lipid- and glucose-lowering properties in a single molecule, assisting in the reduction of blood triglycerides and glucose levels. Additionally, it aids in the reduction of insulin resistance. Lipaglyn has an improved safety profile, increased lipid-regulating activity, and excellent glycemic control.

Use Instructions

Take Lipaglyn at the same time each day, with or without food. Lipaglyn should be swallowed whole with a glass of water; the tablet should not be broken or chewed. Your doctor will choose the duration of your Lipaglyn treatment based on your medical condition.

Storage Keep out of direct sunlight and in a cool, dry area.

Lipaglyn Adverse Reactions

Gastroenteritis (stomach inflammation)

Nausea

Vomiting

Atherosclerosis (weakness)

Discomfort in the chest

Dizziness

Phenomenon (fever)

Adverse Drug Reactions

Saroglitazar should not be taken if you are allergic to any of the ingredients. Notify your physician if you experience rapid weight gain. If you are pregnant, see your doctor before using Saroglitazar. Saroglitazar is not known to be eliminated in breast milk; hence, nursing women should avoid using Saroglitazar. Saroglitazar should not be given to minors due to the lack of documented safety and efficacy. Saroglitazar may produce dizziness, therefore exercise caution while driving. Consume no alcohol while taking Saroglitazar as it may produce unpleasant side effects. Saroglitazar should be taken with caution in type-2 diabetic patients who also have cardiovascular problems.

Interactions Between Drugs

Interactions Between Drugs: None discovered/established.

Interactions between Drugs and Foods: None discovered/established.

Interactions Between Drugs and Diseases: None discovered/established.

Safety Recommendations

ALCOHOL

To avoid undesirable side effects, it is recommended that you abstain from alcohol while using Saroglitazar.

PREGNANCY

Saroglitazar is classified as a pregnancy category C drug. If you are pregnant, see your doctor before using Saroglitazar; your doctor will prescribe only if the benefits outweigh the hazards.

BREAST FEEDING

Nursing moms should avoid Saroglitazar because it is unknown whether the medication is excreted in breast milk.

DRIVING

Dizziness is a possible side effect of Saroglitazar. As a result, drive or operate machines only when alert.

LIVER

SAROGLITAZAR SHOULD BE USED WITH CAUTION IN PATIENTS WITH LIVER Illness Saroglitazar should be used with caution in patients with liver disease. Consult your physician if you have a liver impairment or have any concerns about this.

KIDNEY

In people with kidney illness, saroglitazar should be administered with caution. Consult your physician if you have kidney impairment or have any concerns about this.

Advice on Diet and Lifestyle

Adhere to a cholesterol-reducing diet.

Exercise on a regular basis. It aids in weight maintenance and cholesterol reduction.

Consume less salt and sugar.

Avoid smoking and consuming alcohol.

Select healthy fats and avoid trans fats.

Include omega-3 fatty acids, high-fiber foods, and fruits and vegetables in your diet.

Participate in any physical exercise that you enjoy, such as swimming, brisk walking, or jogging. Take the stairs rather than the elevator/lift.

Consume food in regular intervals. Avoid skipping meals. Additionally, avoid overeating.

Complement your treatment with Saroglitazar with a nutritious diet and at least 45 minutes of walking.

Maintain good rest and avoid stress through meditation or yoga.

Additionally, this item is non-returnable.

Concern for Patients

Diabetic dyslipidemia/hypertriglyceridemia: Diabetic dyslipidemia, sometimes referred to as hypertriglyceridemia, is characterized by elevated triglyceride, low-density lipoproteins (LDL), and decreased high-density lipoprotein (HDL) levels. This is a common complication of type-2 diabetes mellitus. It is a significant risk factor for heart disease in diabetes people. Dyslipidemia may be caused by lifestyle factors, genetics, obesity, a high saturated/trans fat diet, hypothyroidism, or kidney disease. Chest pain/tightness, indigestion, heartburn, dizziness, palpitations, shortness of breath, cold sweats, nausea, and vomiting are all symptoms of diabetic dyslipidemia.

FAQs

Saroglitazar lowers triglycerides and low-density lipoprotein (LDL) cholesterol while increasing HDL cholesterol. Additionally, it aids in glucose utilization. Saroglitazar accomplishes this by reducing insulin resistance and lowering blood lipid and glucose levels.

Saroglitazar is not associated with weight gain or edema. However, consult your physician if you experience rapid weight gain. Your physician may perform a physical examination to check for fluid accumulation, volume-related problems such as oedema, and congestive heart failure.

Consult your doctor before discontinuing Saroglitazar. Continue taking Saroglitazar for as long as your doctor prescribes it to effectively treat your problem.

Saroglitazar may be taken by older persons with a doctor’s prescription. Saroglitazar, on the other hand, should be taken with caution in senior individuals.

Consult your physician before to using Saroglitazar if you have a history of heart issues. Saroglitazar should be taken cautiously in individuals with type-2 diabetes who have heart-related complications such as episodic congestive heart failure if recommended. In such patients, it is recommended to check for signs and symptoms of congestive heart failure on a regular basis.