Macitent is an anti-hypertensive medication that is primarily used to treat excessive blood pressure in the arteries of the lungs (pulmonary arterial hypertension). Hypertension is a medical disease in which blood pressure (the force exerted by circulating blood) is excessively high on the walls of blood vessels. The heart has to work harder to pump blood throughout the body as a result of this illness. The arteries in the lungs and the right side of the heart are affected by pulmonary hypertension.
Macitent contains a chemical called’macitentan,’ which works by blocking Endothelin, a natural substance that constricts blood vessels and elevates blood pressure. Macitent improves blood supply and expands restricted pulmonary arteries (blood vessels that deliver blood from the heart to the lungs), decreasing blood pressure.
Follow your doctor’s instructions for taking Macitent. Your doctor will determine the dosage and duration of Macitent based on your medical condition. Headaches, airway irritation, and oedema are all possible side effects. The majority of Macitent’s negative effects do not require medical treatment and fade away with time. If the adverse effects do not go away, please see your doctor.
If you’re using any prescription or non-prescription medications, including vitamins or herbal supplements, please let your doctor know. If you have any allergic reactions to Macitent or other medicines, tell your doctor before you start using it. If you have low blood pressure, lung, heart, kidney, liver, or liver problems, or if you have anemia, tell your doctor (lack of blood cells). If you are pregnant or breastfeeding, you should seek medical advice. Stopping Macitent without visiting your doctor could make your situation worse and put you at risk for future cardiac problems. Alcohol should not be consumed while taking Macitent because it may raise the risk of low blood pressure.
Pulmonary arterial hypertension (PAH) in adults is treated with Macitent.
Macitent is an antihypertensive drug used to treat excessive blood pressure in the arteries of the lungs (pulmonary arterial hypertension, or PAH). It contains the ingredient ‘Macitentan,’ which works by blocking Endothelin, a natural substance that constricts blood vessels and elevates blood pressure. The pulmonary arteries narrow in persons with PAH, making it more difficult for the heart to pump blood through them. Macitent opens up these narrowed arteries, making it easier for the heart to pump blood and decreasing blood pressure.
Macitent should be taken whole, with a glass of water, with or without food, or as advised by your doctor. The tablet should not be crushed or chewed.
Store in a cool, dry location away from direct sunlight.
Macitent Side Effects
Anemia (low red blood cell count) or hemoglobin deficiency
Bronchitis is the inflammation of the bronchial tubes (inflammation of the airways)
Nasopharyngitis (nasopharyngitis) is a (inflammation of the throat and nasal passages)
Swelling, especially in the ankles and feet, is known as oedema.
Please let your doctor know if you are allergic to Macitentan or any other medications. Before using Macitentan, tell your doctor if you have heart failure, liver or kidney disease, lung problems (pulmonary fibrosis), anemia, oedema (fluid retention), or hypotension (low blood pressure). Macitentan is not recommended during pregnancy since it is detrimental to the fetus. Before starting Macitentan, please get a pregnancy test. Before taking Macitentan, make sure you have a negative pregnancy test. Also, if you’re using Macitentan, make sure you’re using effective birth control to avoid getting pregnant. If you’re a breastfeeding mother, talk to your doctor before taking Macitentan. To avoid disease recurrence, follow the doctor’s instructions to the letter, even if you feel better. Macitentan may produce dizziness and weakness, impairing your ability to concentrate and drive. Do not drive or operate machinery while taking it. Alcohol should be avoided when taking Macitentan since it increases the risk of low blood pressure. Macitentan is not indicated for patients under the age of eighteen.
Interactions Between Drugs
Interactions between drugs: Antibiotics (e.g. rifampicin, clarithromycin), phenytoin (e.g. phenytoin), carbamazepine (e.g. carbamazepine), anti-fungal medicines (e.g. fluconazole, itraconazole), amiodarone (e.g. amiodarone), cyclosporine (e.g. cyclosporine), anti-fungal medicines ( (e.g. diltiazem, verapamil).
Drug-Food Interactions: Macitentan’s adverse effects may be exacerbated by alcohol. As a result, it’s best to avoid drinking alcohol when taking Macitentan.
Drug-Disease Interactions: Before taking Macitentan, anyone who have heart failure, liver or renal disease, lung disorders (pulmonary fibrosis), anemia, edema (fluid retention), low blood pressure, or severe dehydration should visit their doctor.
Alcohol consumption with Macitentan should be limited because it may increase the risk of low blood pressure and induce side effects such as dizziness, fainting, light-headedness, or headache.
Macitentan should not be used during pregnancy. It has the potential to affect and harm a developing fetus. Before you start using Macitentan, you should have a pregnancy test. Before taking Macitentan, make sure you have a negative pregnancy test. Also, if you’re using Macitentan, make sure you’re using effective birth control to avoid getting pregnant.
Consult your doctor; there hasn’t been much research done on the usage of Macitentan in breastfeeding or nursing women.
Macitentan has a number of negative effects, including headaches and hypotension, and the symptoms of your disease may render you unable to drive.
If you have a history of liver illness or very high levels of liver enzymes in your blood, tell your doctor before using Macitentan. Before prescribing Macitentan, your doctor will consider the advantages as well as any potential hazards.
Before taking Macitentan, see your doctor if you have kidney problems. In people with kidney difficulties, macitentan may cause blood pressure to drop even more and hemoglobin levels to drop. Before ordering Macitentan, please see your doctor, who will assess the advantages and any potential hazards.
No habit formation
Advice on Diet and Lifestyle
Vegetables, fruits, whole grains, legumes, omega-3-rich meals, and lean protein sources should all be part of your diet.
Maintain a BMI of 19.5-24.9 to keep your weight under control.
Chronic stress can raise your blood pressure, so avoid it. To cope with stress and practice mindfulness techniques, try to appreciate and spend time with your loved ones.
Include heart-healthy omega-3-fatty acid-rich foods and beverages in your daily diet. To lower your blood pressure, you can also use low-fat cooking oils like olive oil, soybean oil, canola oil, and coconut oil.
Limit your salt intake to no more than 2,300 mg per day.
Alcohol should be consumed in moderation or not at all.
The best way to reduce your risk of heart disease is to stop smoking.
Keep an eye on your blood pressure on a daily basis, and if you detect any changes, see a doctor.
If your doctor suspects you have anemia, he or she may order a blood test (a reduced number of red blood cells).
Macitentan may impact your blood sugar levels if you have diabetes. Notify your doctor so that your diabetic medication can be adjusted accordingly.
To control your blood pressure, your dietician may recommend an appropriate activity regimen and nutrition.
A liver function test may be recommended by your doctor.
Additional Information : This item is non-refundable.
Concerns of Patients
High blood pressure in the blood vessels (pulmonary arteries) that convey blood from the heart to the lungs is referred to as pulmonary arterial hypertension. It’s a dangerous condition that might cause damage to the right side of the heart. Blood flow through the pulmonary arteries becomes more difficult when the walls thicken and harden. The right side of the heart has a harder time pumping blood through the arteries because of the lower blood flow, which can lead to heart failure. Shortness of breath, dizziness, palpitations, and chest pressure are all common signs of pulmonary hypertension. It can affect people of all ages, although it is more likely among persons who have already been diagnosed with a heart or lung condition.
Macitent is made up of Macitentan. It’s an anti-hypertensive drug that works by expanding the pulmonary arteries and improving the heart’s ability to pump blood efficiently.
Even if you’re in a good mood, keep employing the $ symbol. It should be taken exactly as advised by your doctor to avoid recurrence of symptoms and illness worsening.
In situations of allergic reactions, heart failure, liver, renal disease, lung problems (pulmonary fibrosis), anemia, oedema (fluid retention), and hypotension, macitentan should be taken with caution (low blood pressure).
Shortness of breath, exhaustion, faintness, dizziness, chest discomfort (angina), palpitations, and swelling (oedema) in the legs, ankles, feet, or stomach are all frequent symptoms of pulmonary hypertension (abdomen).
Although there is no cure for pulmonary hypertension, there are therapies that can help you manage your symptoms and manage your condition. If the cause is identified and treated early enough, irreparable damage to your pulmonary arteries (blood vessels that supply your lungs) may be avoided.