Macpee is a member of the ‘Cholinergic agents’ class of drugs that are used to treat urinary retention (holding urine in the bladder) caused by surgery, childbirth, or bladder muscle issues.
The Macpee contains ‘bethanechol,’ which acts on the bladder muscles to aid alleviate inability to urinate. It activates the detrusor muscle (a bladder muscle), which pushes the urine out of the bladder and initiates the urination process.
Macpee comes in two forms: an oral tablet and an injectable. The tablet should be swallowed whole with a glass of water. The tablets should not be crushed, chewed, or broken. Do not self-administer the injection; it is administered by a healthcare professional. Abdominal discomfort, nausea, diarrhea, a strong desire to pee, increased salivation, flushing (reddening of the skin), and sweating are all possible side effects. If these adverse effects do not go away or worsen, see a doctor.
If you are allergic to bethanechol or any of the other ingredients, do not take Macpee. If you have had surgery or have been previously diagnosed with gastrointestinal (stomach and intestine) difficulties, urinary blockages, asthma, heart disorders, hyperthyroidism, seizures, Parkinson’s disease, or blood pressure problems, tell your doctor before using Macpee (low or high). Also, let your doctor know if you’re pregnant or nursing. If Macpee is prescribed, avoid drinking alcohol while taking it because the condition may deteriorate as a result of the increased risk of negative effects. Because Macpee might produce dizziness, it’s best if you avoid activities that require you to be alert, such as driving or operating heavy machinery.
Macpee Urinary Retention’s Applications
Macpee is a cholinergic medication that helps with urinary retention. It acts by pushing urine out of the bladder by acting on the detrusor muscle (bladder muscle). The detrusor muscle contracts sufficiently to initiate micturition (urination) and thereby empty the bladder.
Macpee comes in two forms: an oral tablet and an injectable. Oral tablet: Your doctor will determine the dose and duration based on your medical condition. Do not crush, chew, or break the tablet; it should be eaten whole with a glass of water. To avoid nausea, take the tablets 1 hour before or 2 hours after eating. Do not self-administer injections, which are delivered with a syringe by a healthcare professional.
Store in a cool, dry location away from direct sunlight.
Macpee Adverse Effects Abdominal discomfort, nausea, diarrhea, a strong desire to urinate, excessive salivation, flushing (reddening of the skin), and sweating are all possible side effects of Macpee. If these adverse effects do not go away or worsen, see a doctor right soon.
If you are allergic to any of the ingredients in Bethanechol, don’t take it. If you have recently had surgery, stomach or intestinal ulcers, bladder obstruction, peritonitis (infection of the stomach lining), or inflammatory bowel disease, tell your doctor before using Bethanechol (inflammation of the digestive tract). The use of Bethanechol in the above illnesses could make things worse. In hyperthyroid people, bethanechol may cause atrial fibrillation (heart rhythm disorders) (overactive thyroid). When taken in people with lung disorders such as asthma or chronic obstructive pulmonary disease (COPD), bethanechol might cause symptoms to worsen because it constricts the airways. Patients with heart disease, hypotension (low blood pressure), bradycardia (low heart rate), seizures, or Parkinson’s disease should not take Bethanechol. Alcohol should not be consumed because it can cause dizziness. If you are pregnant or breastfeeding, tell your doctor. Standing up carefully from a sitting or sleeping posture will help you avoid dizziness from this drug.
Interactions Between Drugs
Bethanechol’s effectiveness may be affected by the use of other cholinergic or anticholinergic medicines, as well as antihypertensive treatments (mecamylamine and trimethaphan).
There were no drug-food interactions discovered.
Bethanechol should be used with caution in patients who have urinary bladder obstruction, inflammatory bowel diseases (intestinal inflammation), hyperthyroidism (overactive thyroid), stomach ulcers, lung problems, bradycardia (slow heart rate), hypotension (low blood pressure), coronary artery disease (heart disease), seizures (fits), and Parkinson’s disease (a brain disorder).
Alcohol may increase the likelihood of negative side effects. As a result, avoid consuming alcohol while using Bethanechol.
Bethanechol is classified as a category C drug. It should only be used in pregnant women if absolutely necessary.
Only if absolutely necessary, should Bethanechol be given in breastfeeding moms.
Bethanechol can make you dizzy. So, if you’re on Bethanechol, don’t drive or operate heavy machinery.
In patients with liver problems, Bethanechol should be administered with caution.
In patients with kidney illness, Bethanechol should be administered with caution. It’s possible that you’ll need to modify your dosage.
No habit formation
Advice on Diet and Lifestyle
In the morning and afternoon, rather than at night, drink more fluids.
Caffeine and alcohol should be consumed in moderation.
Maintain a healthy body mass index (BMI). If you are overweight or obese, you should lose weight.
Consume a nutritious diet rich in whole grains, fruits, and vegetables.
Additional Information: This item is non-refundable.
Concerns of Patients
The inability to empty the bladder is known as urinary retention. It occurs when the urinary tract is obstructed or when the bladder muscles are weak as a result of surgery, childbirth, or other underlying problems.
Urinary retention, or the inability to urinate, is treated with bethanechol. It tightens the bladder muscles and starts the urine process, emptying the bladder.
Bethanechol can produce dizziness and reduced blood pressure (hypotension). It is recommended that you stand up gently when rising from a sitting or laying posture to avoid falling.
For the use of Bethanechol in pregnant women, there are insufficient safety data. As a result, Bethanechol should only be used in pregnant women if clinically necessary.
It is best to take a Bethanechol pill first thing in the morning. To avoid nausea, take 1 hour before or 2 hours after eating.
Bethanechol can cause asthma symptoms to flare up by narrowing the airways. As a result, it is not advised for use in asthmatic patients.