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NATRILIX 2.5MG Indapamide – 10 Tablets


Brand Name: Natrilix

Name:  Indapamide 

Strength: 1.5  mg

Pills per order:  10 Pills

Production Company:  Serdia Pharmaceuticals 

Used for:   Thiazide Diuretic, Prevention of absorption of excess salt

About Natrilix

Natrilix 2.5 mg belongs to a group of medicines “thiazide diuretic” primarily used for the treatment of hypertension (high blood pressure). Additionally, Natrilix 2.5 mg is used to reduce the risk of heart failure and oedema (a build-up of fluid in the body). Thiazide diuretic prevents the body to absorb an excessive amount of salt that may cause fluid retention in the body. Hypertension is a medical condition, in which the blood exerts high pressure against the walls of blood vessels. Due to this, the heart has to work harder to pump the supply of blood in the whole body. Hypertension can put a person on severe health complications, including stroke, heart failure, heart attack, and aneurysm.

Natrilix 2.5 mg contains Indapamide, and it is only available on prescription. It works by inhibiting the reabsorption of sodium in the body, resulting in an increase in chloride, sodium, and water excretion through urine. The shift in electrolytes and sodium level reduces the vascular resistance and makes the heart work normally. The production of diuresis and removal of excessive salt and fluid helps to lower down the blood pressure.

Natrilix 2.5 mg is an orally administered drug. You can take Natrilix 2.5 mg with food or without food. It should be swallowed whole with a glass of water. Do not chew, bite, or break it. Your doctor will advise you how often you take your tablets based on your medical condition. In some cases, you may experience dehydration, dizziness, headache, fatigue, nausea, itching, and abdominal pain. Most of these side effects of Natrilix 2.5 mg do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Natrilix 2.5 mg should not be stopped even if you feel better, without consulting your doctor as stopping a sudden intake of Natrilix 2.5 mg may worsen your condition and increase the risk of future heart problems. Natrilix 2.5 mg may lower down the potassium level in the body, so ask your doctor about how to add it to the diet. Please inform your doctor if you have had an allergic reaction to Natrilix  Tablet, is pregnant or get pregnant, is breastfeeding, have gout, liver disease, kidney problems, heart failure, diabetes, a heart valve problem, or heart attack.

Uses of Natrilix  Tablet:   Hypertension (high blood pressure)

Medicinal Benefits

Natrilix 2.5 mg is prescribed for treating high blood pressure. Being a diuretic medication, Natrilix 2.5 mg enhances the excretion of sodium and water through urine by restricting the absorption of sodium in the tubes of the nephron. If high blood pressure is not controlled for a longer time, then arteries and the heart will not be able to function properly. This may further increase the chances of damage of blood vessels of the brain resulting in heart attack, serious kidney failure. However, taking Natrilix 2.5 mg at the right time can control the blood pressure and make the heart function properly.

Directions for Use

Natrilix 2.5 mg is an oral medication that needs to be taken by mouth. Natrilix 2.5 mg can be taken with or without food as suggested by the doctor, usually once a day. Being a diuretic medication, if a person takes Natrilix 2.5 mg too close to bed-time, then they need to wake up in the night to urinate. Therefore, one should maintain a gap of at least 4 hours between intake of Natrilix 2.5 mg and sleep time. Never stop or start the Natrilix 2.5 mg without asking with the doctor as it may require at least 3-6 weeks to see a lowering of blood pressure.


Store in a cool and dry place away from sunlight

Side Effects of Natrilix  Tablet

Like all medicines, Natrilix 2.5 mg can also cause side effects, although not everybody experiences them. Dizziness, blurred vision, fatigue, nausea, abdominal pain, dry mouth, headache, constipation, diarrhoea, itching, rashes, shortness of breath are common side effects of Natrilix  Tablet. These side-effects may occur in the initial days of starting the course and will improve with time, as the body is adjusting to this medication. If any of these side effects worsen or do not get improved, then notify to doctor. Depending on your medical condition, your doctor will decide how long you need to take Natrilix  Tablet.

Drug Warnings

Natrilix 2.5 mg can increase the chances of light-headedness so rise slowly if you are sitting and avoid operating any machine or doing any work that needs mental alertness. Before taking Natrilix  Tablet 10’s, tell the doctor if you have any allergies to the active and inactive ingredients present in it, have a history including anuria (kidneys aren’t producing urine)/ renal dysfunction, fluid or electrolyte imbalance, liver disease, lupus erythematosus (an autoimmune inflammatory disease-causing scaly red patches on the skin), and asthma. Natrilix 2.5 mg may lower down the potassium level in the body, so ask the doctor about how to add it to the diet. Natrilix 2.5 mg should only be given during pregnancy when the doctor strongly suggests it. Natrilix 2.5 mg could pass in the breast milk so ask your doctor before taking it, if you are a breastfeeding woman. Natrilix 2.5 mg should not be given to children as safety has not been established.

Drug Interactions

Drug-Drug Interaction: Natrilix 2.5 mg may interact with other diuretic medications (furosemide, torsemide), antihypertensive drugs (ramipril, amlodipine, baclofen, levodopa, clonidine), a medicine used to treat bipolar disorder (lithium, risperidone, amisulpride), painkillers (ibuprofen, naproxen), and blood thinners (warfarin).

Drug-Food Interaction: Natrilix 2.5 mg can be taken with or without a meal. However, it should be taken early in the day and at the same time of day. It is best to avoid heavy meals with Natrilix 2.5 mg as it will make medicine to work effectively. However, one should tell their doctor if they are using multi-minerals or any ayurvedic supplements. It is best to limit the intake of salt.

Drug-Disease Interaction: Natrilix 2.5 mg can interact with certain diseases. Hence, it is advisable to tell the doctor about the past or current medical history including anuria (kidneys are not producing urine)/ renal dysfunction, fluid or electrolyte imbalance, liver disease, lumps erythematosus (an autoimmune inflammatory disease-causing scaly red patches on the skin), and asthma.

Safety Advice


It is best to avoid or limit alcohol intake. Alcohol may aggravate the side effects and may cause a sudden drop in blood pressure and dizziness.


The use of Indapamide is not allowed during pregnancy until or unless prescribed by the doctor. Indapamide can only be used during the pregnancy if the benefits of Indapamide are more in comparison to the risks.


Indapamide tends to pass in the breast milk, so talk to your doctor before taking this medicine. A high dose of Indapamide may reduce the production of milk so never take it without consulting with a doctor.


Indapamide could make a person feel dizzy or drowsy. Therefore it is advised to avoid driving or doing any task that needs a clear vision.


Indapamide should be taken with caution as this is a diuretic medicine so, if a person is already dealing with liver disease, then Indapamide may cause serious loss of potassium from the body resulting in vomiting or diarrhoea.


Indapamide could cause a high level of nitrogen in the body. If a person is finding trouble urinating then the doctor will not allow the usage of Natrilix  Tablet 10’s. However, the usage of Indapamide is contraindicated in patients whose kidneys are unable to produce urine.

Habit Forming :   No

Diet & Lifestyle Advise

Cut back the foods high in saturated fat, sugar, and cholesterol.

Include more whole grains foods and nuts in your diet.

Include more vegetables, fruits, and low-fat dairy products in your diet.

Follow the instructions of your doctor as they will suggest you include, regular exercise, intake of a low sodium diet in your daily life.

Increase the intake of potassium-rich foods, including prunes, raisins, and orange juice in your diet as it will help the body to recover at a fast rate.

Limit consumption of excessive sodium, sugary drinks. For cutting back on sodium, start by reducing the sodium intake to 1500 mg (about 2/3 teaspoon) and then gradually reduce it more.

Instead of munching chips or sweets, eat unsalted nuts and frozen yoghurt that is very good for health and keep the weight under control.

Check your weight at regular intervals so that you can keep your eyes on weight fluctuation. Try to control your weight according to BMI, so include exercising and healthy eating habits in your lifestyle.

Make a habit of regular exercising for at least 1-2 hours a day, or at least one should walk about half an hour for good health. Doing this will lower down the sugar level and maintain a normal heart rate.

Stress can worsen hypertension, so one should enjoy their time with their friends and should include mindful activities in their daily routine.

Please keep a record of blood pressure as it will help a person to notice the fluctuations in their blood pressure.

Special Advise

It is best to limit salt intake and include high fibre foods in the diet.

Other Information:   This item is Not Returnable.

Disease/Condition Glossary

Hypertension: It is a chronic condition when blood pressure is too high. Blood pressure is defined as the amount of blood pumped by the heart and the amount of resistance exerted by the arteries against the blood flow.  If the heart pumps more blood, then arteries become narrower, and in turn, blood pressure becomes high.  If blood pressure becomes uncontrolled, then it may cause serious heart disease, including stroke and heart attack. Additionally, high blood pressure also causes brain damage (stroke), and kidney failure. Blood pressure is expressed by systolic and diastolic. Systolic blood pressure represents the contraction and relaxation of the heart. Diastolic represents the pressure in the vessels when the heart beats and in a resting state. Ideal blood pressure should be between 90/60mmHg and 120/80mmHg. Hypertension is detected when systolic blood pressure is more than 140mmHg, and diastolic pressure is higher than 90mmHg. Some of the symptoms of hypertension include headache, nose bleed, vomiting, and chest pain.

Oedema: Swelling in the body parts such as ankles, feet, and legs is often caused by a build-up of fluid in these areas, called oedema.


Indapamide belongs to the group of medicines called diuretics that increase the amount of urine that is passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. Thus, it helps to lower high blood pressure, reducing the chances of heart attack or stroke.

Unless suggested by the doctor, to take Indapamide in morning or night, one should fix a time slot, and they should take it regularly at the same time. However, one should avoid taking it at night time or just before bed as this medicine causes frequent urination. So, best to take it before 4 hours going to bed.

As hypertension is a serious medical issue, so taking Indapamide help to reduce the risk of heart disease and other serious conditions. So, one should not stop taking medicine without consulting with their doctor. However, depending upon the condition, the doctor will adjust the dosing.

Even if a person achieved their goal of bringing their blood pressure back to normal, they should not stop taking it without asking a doctor. Only after the doctor’s recommendation, the dosage of Indapamide could be adjusted.

Prolonged intake of Indapamide may decrease your potassium levels in the bloodstream. So, it is better to ask your doctor about foods high in potassium like bananas or orange juice. Besides this, consult a doctor regarding the use of table salt or sodium chloride, or salt substitute containing potassium.

Indapamide comes under the category of diuretics, so it is formulated to increase the amount of water in the body to expel the excessive sodium present in the body through urine. In this way, it helps to maintain normal blood pressure.

Additional information

Chemical Name


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